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Abstract:

Aim: was to analyze own experience of differential diagnostics of cardiac tumors by using cardiac CT.

Materials and methods: 354 cardiac CT were made in «Fedorovich Klinikasi» in 2011-2017. The age of patients ranged from 5 month to 69 years (mean 27,2). There were 200(56,5%) men and 154 (43.5%) women. The study was carried out on MDCT scanners Brilliance 64 and Brilliance i-CT 256 (PHILIPS). Iodine containing contrast agent «Unihexol 350» was injected intravenously by means of «Ulrich» automatic injector.

Results: primary benign cardiac masses were detected in 10(2,8%) cases. Most of them were myxomas - 6 cases (60%), located in the left atrial cavity in 2 cases, in the mitral valve region - in 1, in the right atrium - in 2, and in the right ventricle - in 1case. Cardiac lipomas were detected in 2 (20%) patients. Papillary fibroelastoma of the aortic valve (1 case) and rhabdomyoma of the right

ventricle (1 case) also occurred in our study Intracardiac spreading of malignant neoplasms was noted in 5(1,4%) patients. Thrombosis of cardiac chambers was found in 7(2%) patients.

Conclusion: cardiac CT provides useful anatomical and functional information in evaluating cardiac masses, providing an accurate picture of the disease, allowing to assess localization and structure of the tumor, the condition of the tumor-free heart chambers, mediastinum, and lungs.

 

References

1.      Yuan SM, Shinfeld A, Lavee J, Kuperstein R, Haizler R, Raanani E. Imaging morphology of cardiac tumors. Cardiology Journal. 2009; 16 (1): 26-35.

2.      Puchkova EN, Sibirskiy VY Goncharova MA, Gajonova VE. Imaging diagnostics of the primary cardiac tumors. Kremlyovskaya meditsina. Klinicheskiyvestnik. 2009; 3: 7476 [In Russ].

3.      Colucci WS, Schoen FJ, Braunwald E. Primary tumors of the heart. 5th ed In: Brauwald E, editor., Heart Disease. A Textbook of Cardiovascular Medicine. Philadelphia, PA: WB Saunders; (1998). p. 1464-78.

4.      Roever L, Dourado PM, Resende ES, Chagas AC. Cardiac Tumors: A Brief Commentary Front Public Health. 2014; 2:264.

5.      Konradi YV, Ryzhkova DV. Imaging diagnostics of cardiac tumors. Translyatsionnaya meditsina. 2015; 2(4): 28-40 [In Russ].

6.      Kassop D, Donovan MS, Cheezum MK, Nguyen BT, Gambill NB, Blankstein R, Villines TC. Cardiac Masses on Cardiac CT: A Review. Curr Cardiovasc Imaging Rep. 2014; 7:9281

7.      Angulo CD, Diaz CM, Garcia ER, Fernandez RS, Siso AR, Diaz MM. Imaging findings in cardiac masses (Part I): Study protocol and benign tumors. Radiologia. 2015; 57(6):480-488.

8.      Grebenc ML, Rosado-De-Christenson ML, Green CE, et al. Cardiac myxoma: imaging features in 83 patients. Radiographics. 2002; 22: 673-89.

9.      Yu K, LiuY Wang H, Hu Sh, Long C. Epidemiological and pathological characteristics of cardiac tumors: a clinical study of 242 cases. Interactive Cardio Vascular and Thoracic Surgery. 2007; 6: 636-639.

10.    Butany J, Nair V, Naseemuddin A, Nair G, Catton C, Yau T. Cardiac tumors: diagnosis and management. Lancet Oncol. 2005; 6:219-228.

11.    Cheezum MK, Jezior MR, Carbonaro S, Villines TC. Lipomatous hypertrophy presenting as superior vena cava syndrome. J Cardiovasc Comput Tomogr. 2014.

12.    Howard RA, Aldea GS, Shapira O.M, et al. Papillary fibroelastoma: Increasing recognition of a surgical disease. Ann Thorac Surg. 1999;68:1881-5.

13.    Ghadimi Mahani M, Lu JC, Rigsby CK, Krishnamurthy R, Dorfman AL, Agarwal PP. MRI of pediatric cardiac masses. AJR Am J Roentgenol. 2014;202:971-81.

14.    Bussani R, De-Giorgio F, Abbate A, Silvestri F. Cardiac metastases. J Clin Pathol 2007; 60:27-34.

15.    Goldberg AD, Blankstein R, Padera RF Tumors metastatic to the heart. Circulation. 2013; 128: 1790-4.

16.    Kim DH, Choi S, Choi JA, Chang JH, Choi DJ, Lim C. Various findings of cardiac thrombi on MDCT and MRI. J Comput Assist Tomogr. 2006;30:572-577.

17.    Scheffel H., Baumueller S., Stolzmann P., et al. Atrial myxomas and thrombi: comparison of imaging features on CT. Am J Roentgenol. 2009;192: 639-45.

 

Abstract:

Aim: was to increase diagnostic value of cardiac CTA (CCTA) by estimation of the CCTA informative value in CA (Coronary arteries) diseases and optimization of OOTA procedure for reducing of radiation dose (RD).

Materials and methods: CCTA informative value in CA diseases was assessed on the base of data of 200 patients (average age of patients was 60,4 (from 35 to 80 years), men/women ratio: 1.94:1(132/68). Parameters of coronary stenosis severities: its localization, extension, degree and characteristics of coronary stenosis. The study was performed with GE Optima 660 128-slice scanner and Missouri Ulrich injector with bolus injecting 60-100 ml of nonionic contrast media (350 mg/ml) at 4-6 ml/sec injector rate. For data processing used: «Auto Coronary Analysis» and «Auto Ejection Fraction» programs at - AW5 workstation.

Results: discovered various severity degrees of atherosclerotic lesions based stenosis intensity up to 50% (46 /23,5%), 50-60% (65/33%), 60-70% (35/17,9%), 70-80% (26/13,5%), 80% and more (23/11,8%). CCTA data coincided with conventional coronary angiography in 89% cases. RD decreasment was achieved by: pitch change depending on heart rate, scan area optimization (reduction), kV and mAc with radiation exposure decline in CCTA to 7,0-8,0 mSv In pitch value increasing to 1,48 - RD decreased to 45% (20 mSv). In prospective synchronization with ECG, RD decreased to 65% (7-12 mSv) as X-Ray tube radiates the highest RD at 70% cardiac cycle phase (120kV/180-200mAc), in other phases (80kV/100 mAc) RD values were lower.

Conclusion: CCTA is a valid non-invasive method in CA pathology diagnostics enabling accurate identification of stenosis location, extent, degree and characteristics. Scanning protocol individualization in CCTA enables significant reduce of RD.

 

References

1.     Kurbanov R.D., Urinov O. Profilaktika osnovnyh faktorov riska osnova snizheniya smertnosti ot serdechnososudistyh zabolevanij. [Prophylaxis of major risk factors-basis of reduction of mortality caused by cardiovascular diseases.] Zdravoohranenie Uzbekistana. 2011; 41, 1-2. [In Russ].

2.     Boguneckiy A.A. Vozmozhnosti magnitno-rezonansnoj tomografii serdca s kontrastnym usileniem v prognozirovanii posleoperacionnoj dinamiki u pacientov s ishemicheskoj bolezn'yu serdca. [Possibilities of cardiac MRI with contrast enhancement in prognosis of post-surgical dynamics in patients with ischemic cardiovascular disease.] Rossiyskiy elektronnyiy zhurnal luchevoy diagnostiki. 2012; 85-86. [In Russ].

3.     Multi-slice and Dual-source CT in Cardiac Imaging. Eds. Ohnesorge B.M., Flohr T.G., Becker C.R. Berlin: Springer. 2006; 359 p.

4.     Fedotenkov I.S., Veselova T.N., Ternovoy S.K., Sinitsyn V.E. Rol' mul'tispiral'noj komp'yuternoj tomografii v diagnostike kal'cinoza koronarnyh arterij. [The role of multispiral computed tomography in the diagnosis of coronary artery calcification.] Cardiologicheskiy vestnik. 2007; II (XIV): 45-48.

5.     Shevchenko I.I. Sravnenie dannyh registrov ostryh koronarnyh sindromov REKORD i REKORD-2: lechenie i ego iskhody v stacionarah, ne imeyushchih vozmozhnosti vypolneniya invazivnyh koronarnyh procedur. [Comparison of the RECORD and RECORD-2 registers data of the acute coronary syndrome: treatment and it’s result in hospitals without ability to carry out invasive manipulations.] Kardiologiya. 2013; 8: 4-10. [In Russ].

6.     Oganov R.G., Pozdnyakov Ju.M., Volkov B.C. Ishemicheskaya bolezn' serdca. [Ischemic heart disease.] M.: Izdatel'skiy Dom Sinergiya, 2002; 308 p. [In Russ].

7.     Ternovoy S.K., Nikonova M.E., Akchurin R.S. et al. Vozmozhnosti mul'tispiral'noj komp'yuternoj tomografii (MSKT) v ocenke koronarnogo rusla i ventrikulografii v sravnenii s intervencionnoj koronaroventrikulografiej. [Possibilities of multispiral computed tomography (MSCT) in assessing of coronary vessels and ventriculography in comparison with interventional coronaroventriculography.] Russian electronic journal of radiation diagnostics. 2013; 3(9): 28-36 [In Russ].

8.     Sinitsyn V.E., Ustjuzhanin D.V. Mul'tispiral'naya komp'yuternaya tomografiya: issledovanie koronarnyh arterij. [Multislice computer tomography: examination of coronary arteries.] Bolezni serdtsa i sosudov. 2006; 1: 20-24. [In Russ].

9.     Coronary Radiology, 2nd edition. Eds. Oudkerk M., Reiser M.F. Berlin: Springer. 2009; 349 p.

10.   Einstein A.J., Elliston C.D., Arai A.E., Chen M.Y. Mather R., Pearson G.D., Delapaz R.L., Nickoloff E., Dutta A., Brenner D.J. Radiation dose from single-heartbeat coronary CT angiography performed with a 320-detector row volume scanner. Radiology. 2010; 254: 698-706.

11.   Vardikov D.F., Yakovleva E.K., Maystrenko D.N. Analiz densitometricheskih pokazatelej koronarnogo rusla pri stenoziruyushchih porazheniyah koronarnyh arterij i posle procedury stentirovaniya metodom ob'emnoj MSKT- koronarografii. [Analysis of densitometric parameters of coronary artery stenosis and after the stenting procedure with the method of volume MDCT coronary angiography.] Luchevaya diagnostika i terapiya. 2015; 3: 53-56. [In Russ].


 

 

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